Serum Endostatin Concentrations Are Higher in Men with Symptoms of Intermittent Claudication

Table 2

Independent risk factors for intermittent claudication in 823 men.

Characteristic	Odds ratio	95% CI	𝑃 value
Serum endostatin (ng/mL)*
<93.00	1.00	Reference
93.00–120.00	2.07	1.15–3.73	0.015
>120.00	1.78	0.98–3.22	0.058
Ever smoking	2.59	1.44–4.67	0.002
Previous stroke	2.12	1.22–3.69	0.008
Dyslipidemia	1.96	1.20–3.20	0.007
Coronary heart disease	1.91	1.20–3.05	0.007
Hypertension	1.77	1.11–2.82	0.016
Age above 76 years^†	1.67	1.07–2.60	0.023
Diabetes mellitus	1.52	0.90–2.58	0.119

For nominal variables the comparisons are to subjects without the risk factor. ∗Men with serum endostatin concentrations in the top and middle tertiles were compared with subjects who had serum endostatin in the lowest tertile. †Approximately median value. All factors listed were included in the multivariate model.