Proteomic Analysis of Serum and Urine of HIV-Monoinfected and HIV/HCV-Coinfected Patients Undergoing Long Term Treatment with Nevirapine

Table 2

List of proteins detected as differentially regulated in serum of patients undergoing long term NVP treatment and normal controls.

Protein name	Database ID number	Protein ID score	Function	Localization	Mass (Da)	Peptide sequence
BAI 1	gi∣2653432	10.04	Cell adhesion	Membrane	857.1950	NATGLILR
BCL2/adenovirus E1B 19 kDa interacting protein	gi∣119573869	2.14	Apoptosis	Nucleus	878.1002	VFRMGPR
Catenin alpha-1	gi∣21411495	6.22	Cell adhesion	Cytoplasm	1492.7295	EYAQVFREHANK
Death-associated protein kinase 3	gi∣4557511	1.79	Apoptosis	Cytoplasm	617.4699	QKGTGK
Zinc finger protein 174	gi∣159163639	7.90	Transcription	Nucleus	742.0348	CLMSSK
Collagen type X11 alpha-1	gi∣1846005	15.77	Cell adhesion	Unknown	1554.9274	GGNTMTGDAIDYLVK
Corin	gi∣4884872	2.91	Protein metabolism	Membrane	1474.3988	WVLTVAHCFEGR
Chondroitin sulfate proteoglycan 4	gi∣124504610	3.64	Carbohydrate metabolism	Membrane	1551.0338	TGKHDVQVLTAKPR
FYVE and coiled domain containing protein 1	gi∣13276231	4.84	Transport	Cytoplasm	874.5961	AALDDQDK
hCG1811779	gi∣119578948	2.12	Others	Unknown	701.1700	LTGPAGGK
hCG2018146	gi∣119595992	1.36	Others	Unknown	815.1358	CLLRPR
hCG2033821	gi∣119618839	2.35	Others	Unknown	707.6396	TATEMR
Obscurin isoform B	gi∣89143259	1.77	Apoptosis	Cytoplasm	1002.3102	KKPGLASFR
Eukaryotic translation initiation factor 4B	gi∣48146033	3.18	Translation	Cytoplasm	828.0649	EPSNPER
Coiled-coil domain containing 146	gi∣23271918	4.84	Cytoskeleton	Cytoplasm	955.2563	ELVVNLLR
Sodium dependent glucose transporter 1	gi∣154937330	5.29	Transport	Membrane	982.5936	HLPETRTK
Microtubule associated protein 1a	gi∣1790878	2.47	Cytoskeleton	Cytoplasm	849.2162	DKDLEXK
Myosin VI	gi∣9280816	1.43	Cell development	Cytoplasm	519.0438	AAAGTK
Peroxisomal trans-2-enoyl-coA reductase	gi∣19923817	7.82	Lipid metabolism	Cytoplasm	846.0755	GAGDLSVVK
Phospholipase B domain containing protein 1	gi∣15029600	3.14	Lipid metabolism	Cytoplasm	927.4162	MMADSGKR
Calmodulin-regulated spectrin-associated protein 2	gi∣44955929	20.38	Cytoskeleton	Cytoplasm	701.6011	AGSLILK
C-type lectin domain family 4 member K	gi∣305410858	12.79	Immune response	Cytoplasm	702.7117	ASALNTK
Zinc finger and BTB domain containing protein 44	gi∣30047807	20.92	Transcription	Nucleus	905.7966	VQDKIFR
RNA exonuclease 1 homolog	gi∣145199237	10.68	DNA replication	Nucleus	821.9409	ASSRDER
Rhesus blood group D antigen	gi∣28629452	6.69	Transport	Membrane	691.7388	VVITLF
Rho-related BTB domain containing 3	gi∣27371219	5.84	Singal	Membrane	1897.7174	CEVMAAMFNGNYMEAK
Solute carrier family 4, sodium bicarbonate cotransporter, member 5	gi∣119620095	24.26	Transport	Membrane	856.6955	SPSSLLPR
Tyrosine-protein phosphate non receptor type 23	gi∣24308073	3.39	Single	Cytoplasm	1008.7161	HVEQVLQR
Zinc finger protein 556	gi∣13376460	4.83	Transcription	Nucleus	710.6905	CGKCGK
Dynactin 1	gi∣4139121	3.52	Transport	Cytoplasm	515.6265	APTAR
Casein kinase I isoform gamma-1	gi∣98986450	7.18	Single	Cytoplasm	685.1477	HIPYR
hCG2045456	gi∣119605796	2.79	Others	Unknown	671.2872	EFNNF
Group IIF secretory phospholipase A2	gi∣145553989	3.89	Lipid metabolism	Cytoplasm	462.4213	ADGAK
hCG2038093	gi∣119602010	3.27	Others	Unknown	613.7015	HVSRD