MicroRNA Expression Profiling in PBMCs: A Potential Diagnostic Biomarker of Chronic Hepatitis C

Table 3

Target miRNAs expression in PBMCs of CHC patients with different HCV genotype and healthy controls.

miRNAs	GT-1	Non-GT-1	Control	value
miR-16	155.065 (10.950)^*	245.167 (25.742)	13.604 (1.713)	<0.001
>1.713	54	15	24
≦1.713	12	5	24
value	0.001
miR-122	0.0016 (0.0002)	0.0000003 (0)	0.0031 (0.0004)	<0.001
>0.0004	17	0	22
≦0.0004	54	20	26
value	<0.001
miR-193b	0.2175 (0.0070)	0.0068 (0.00076)	0.0033 (0.00013)	<0.001
>0.00013	64	13	24
≦0.00013	6	7	24
value	<0.001
miR-199a	1366.614 (513.816)	95.7169 (33.5522)	479.1835 (9.4969)	<0.001
>9.4969	65	13	24
≦9.4969	4	7	24
value	<0.001
miR-214	159.1452 (0.4719)	677.42 (0.5559)	20.2853 (0.2282)	0.943
>0.2282	41	12	24
≦0.2282	26	8	24
value	0.469
miR-222	3.9360 (0.4564)	2.0039 (0.1394)	0.4898 (0.0103)	<0.001
>0.0103	61	18	23
≦0.0103	5	2	24
value	<0.001
miR-324	49.4397 (2.2015)	21.9596 (4.2781)	9.4064 (0.0524)
>0.0524	53	16	24
≦0.0524	12	4	24
value	0.001

PBMCs: peripheral blood mononuclear cells; CHC: chronic hepatitis C.
^*Data were presented by mean (medium).