Prognostic and Biological Significance of MicroRNA-127 Expression in Human Breast Cancer

Figure 4

Upregulation of miR-127 inhibits migration and invasion in BC cells. (a) Scratch wound healing analysis of migration in BC cells. MCF-7/miR-127 (or MCF-7/miR-NC) and SK-BR-3/miR-127 (or SK-BR-3/miR-NC) cells were grown for 3 days and subjected to the wound healing assay. Magnification ×100. (b) Transwell invasion analysis of invasion in BC cells. MCF-7/miR-127 (or MCF-7/miR-NC) and SK-BR-3/miR-127 (or SK-BR-3/miR-NC) cells were grown for 3 days and subjected to the Transwell invasion assay. Magnification ×200. Each experiment was performed at least in triplicate. , versus control.

(a)

(b)