Disease Markers

Research Article

Human Paraoxonase-1 Activity Is Related to the Number of CD4+ T-Cells and Is Restored by Antiretroviral Therapy in HIV-1-Infected Individuals

Table 3

Markers of infection and HIV-1 RNA in HIV-1-infected individuals with highly active antiretroviral therapy (HAART) regimens and ART-naïve.


Parameters⁽¹⁾	HIV-1-infected individuals ()			value⁽²⁾
Parameters⁽¹⁾	ART-naïve ()	EFV or NVP ()	LOP/r ()	value⁽²⁾

CD4+ T-cell (cells/mm³)	404 (205, 443)*	483 (334, 683)	486 (370, 635)	<0.05
CD8+ T-cell (cells/mm³)	955 (643, 1,340)	859 (607, 1,119)	952 (743, 1,215)	ns
CD4 : CD8 ratio	0.4 (0.3, 0.6)	0.5 (0.3, 0.7)	0.5 (0.2, 0.6)	ns
HIV-1 RNA (copies/mL⁽³⁾)	89,266 (±81,572)*	14,121 (±16,224)	16,301 (±20,014)	<0.05

EFV: efavirenz; NVP: nevirapine; LOP/r: lopinavir/ritonavir; ns: no significant difference.
⁽¹⁾Median (interquartile range (IQR) 25%–75%; 95% confidence interval (CI)).
value: comparison between groups by ANOVA and Tukey's honestly significant difference.
⁽³⁾Mean ± standard deviation (m ± SD).
when comparing with other groups.