Variability of the Transferrin Receptor 2 Gene in AMD

Table 3

Distribution of genotypes, frequency of alleles of the c.1892C>T polymorphism of the TFR2 gene, and odds ratios (OR) with 95% confidence intervals (95% CI) in age-related macular degeneration (AMD) patients and controls.

Genotype/allele c.1892C>T	Control; (𝑁=171)	AMD; (𝑁=493)	OR^1) (95% CI)	𝑃^2)	OR^3) (95% CI)	𝑃^2)
	𝑁 (%)	𝑁 (%)
CC	97 (0.57)	267 (0.54)	0.42 (0.32–0.54)↓	<0.001	0.86 (0.6–1.23)	0.411
CT	54 (0.32)	183 (0.37)	1.28 (0.88–1.85)	0.196	1.35 (0.93–1.97)	0.118
TT	20 (0.12)	43 (0.09)	0.72 (0.41–1.27)	0.288	0.71 (0.4–1.26)	0.246
C	248 (0.73)	717 (0.73)	1.01 (0.77–1.33)	0.920	0.99 (0.76–1.29)	0.920
T	94 (0.27)	269 (0.27)	0.99 (0.75–1.3)	0.920	1.01 (0.78–1.33)	0.920

1)Crude odds ratio with 95% confidence interval; ²⁾𝜒² test; ³⁾odds ratio adjusted for age and sex.
Data in boldface are statistically significant.