Comparison of Different Blood Collection, Sample Matrix, and Immunoassay Methods in a Prenatal Screening Setting

Table 1

Average recovery percentage of dried blood spots and finger stick versus conventional venipuncture serum of PAPP-A and fβ-hCG for both immunoassay platforms.

Average % recovery compared to venipuncture serum (± SD)
Platform	Marker	Serum finger prick	DBS venous	DBS finger prick
AutoDELFIA	PAPP-A	103 ± 13	71 ± 12	67 ± 9
Ab-array	PAPP-A	100 ± 10	70 ± 12	72 ± 11
AutoDELFIA	fβ-hCG	103 ± 7	156 ± 56	151 ± 32
Ab-array	fβ-hCG	90 ± 8	137 ± 38	132 ± 34