Research Article
Absence of Correlation between IL-28B Gene Polymorphisms and the Clinical Presentation of Chronic Hepatitis B in an Amazon Brazilian Population
Table 1
Genotypic and allelic frequencies of the polymorphisms rs12979860 and rs8099917 in the IL-28B gene in HBV patients and controls.
| | Polymorphism | HBV group
(%) | Control group
(%) | |
| | rs12979860 | | | | | Genotypes | | | | | CC | 21 (32.3) | 34 (35.0) | 0.5490 | | CT | 27 (41.5) | 46 (47.4) | | TT | 17 (26.2) | 17 (17.6) | | Total | 65 (100.0) | 97 (100.0) | | | Alleles | | | | | C | 69 (53.1) | 114 (58.8) | 0.3694 | | T | 61 (46.9) | 80 (41.2) | | Total | 130 (100.0) | 194 (100.0) | | | | | | |
| | rs8099917 | | | | | Genotypes | | | | | GG | 05 (7.7) | 07 (7.2) | 0.9915 | | GT | 23 (35.4) | 34 (35.1) | | TT | 37 (56.9) | 56 (57.7) | | Total | 65 (100.0) | 97 (100.0) | | | Alleles | | | | | G | 33 (25.4) | 48 (24.7) | 1.00 | | T | 97 (74.6) | 146 (75.3) | | Total | 130 (100.00) | 194 (100.0) | | | | | | |
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aChi-square test.
bHardy-Weinberg law.
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