Research Article
Absence of Correlation between IL-28B Gene Polymorphisms and the Clinical Presentation of Chronic Hepatitis B in an Amazon Brazilian Population
Table 3
Correlation between liver histopathology and the IL-28B gene genotype in chronically infected HBV patients.
| | Liver histopathology METAVIR () | Genotypes of the polymorphism rs12979860 | | Genotypes of the polymorphism rs8099917 | | | CC (%) | CT (%) | TT (%) | GG (%) | GT (%) | TT (%) |
| | Inflammatory activity periportal/periseptal | | | | | | | | | | 0 to 1 | 07 (77.8) | 12 (92.3) | 08 (80.0) | 0.6058 | 04 (100.0) | 10 (83.3) | 13 (81.3) | 0.5394 | | 2 to 3 | 02 (22.2) | 01 (7.7) | 02 (20.0) | — | 02 (16.7) | 03 (18.7) | | Degree of fibrosis | | | | | | | | | | 0 to 2 | 09 (100.0) | 12 (92.3) | 08 (80.0) | 0.3137 | 03 (75) | 11 (91.7) | 15 (93.7) | 0.6738 | | 3 to 4 | — | 01 (7.7) | 02 (20.0) | 01 (25) | 01 (8.3) | 01 (6.3) |
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Notes: conventional signal used: (—) numerical data equal to zero but not as a result of rounding.
a test with Williams’ correction.
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