Mig-6 Gene Knockout Induces Neointimal Hyperplasia in the Vascular Smooth Muscle Cell

Figure 2

Neointima formation is increased in the vascular smooth muscle specific Mig-6 knockout mice. (a) Representative cross sections of balloon-catheter injured femoral artery. Left column, hematoxylin and eosin stain ×200; middle column, hematoxylin and eosin stain ×400; right column, Masson’s trichrome stain ×400. I, intima; M, media; scale bar, 50 m. (b) Quantification of intima to media ratio. for Mig-6 ^f/f mice; for Mig-6 ^d/d mice. .

(a)

(b)