Table 1: KLK6 levels in the plasma of laryngeal SCC patients and controls.

CharacteristicsKLK6 levels (ng/mL) value
MedianInterquartile range

All individuals4.762.34
Diagnostic category
 Healthy4.652.32
 Benign4.651.860.607*
 Cancer4.904.260.047
0.014
Anatomical region of cancer
 Glottis4.914.060.393
 Supraglottis4.884.21
Disease stage
 I + II5.443.600.375
 III + IV4.764.48
T stage
 T16.063.870.544
 T24.985.00
 T34.984.55
 T44.602.62
Lymph node status
 pN05.153.840.507
 pN+4.774.49
Tumor differentiation
 Well4.655.090.637
 Moderate5.334.66
 Poor4.593.85

KLK6: kallikrein 6.
Comparisons of the plasma KLK6 levels between two independent sample cohorts were assessed by the Mann-Whitney test, and those among more than two independent cohorts were assessed by the Kruskal-Wallis test. *Benign versus health; cancer versus benign; cancer versus health.