Table 1: KLK6 levels in the plasma of laryngeal SCC patients and controls.
Characteristics
KLK6 levels (ng/mL)
value
Median
Interquartile range
All individuals
4.76
2.34
Diagnostic category
Healthy
4.65
2.32
Benign
4.65
1.86
0.607*
Cancer
4.90
4.26
0.047†
0.014‡
Anatomical region of cancer
Glottis
4.91
4.06
0.393
Supraglottis
4.88
4.21
Disease stage
I + II
5.44
3.60
0.375
III + IV
4.76
4.48
T stage
T1
6.06
3.87
0.544
T2
4.98
5.00
T3
4.98
4.55
T4
4.60
2.62
Lymph node status
pN0
5.15
3.84
0.507
pN+
4.77
4.49
Tumor differentiation
Well
4.65
5.09
0.637
Moderate
5.33
4.66
Poor
4.59
3.85
KLK6: kallikrein 6. Comparisons of the plasma KLK6 levels between two independent sample cohorts were assessed by the Mann-Whitney test, and those among more than two independent cohorts were assessed by the Kruskal-Wallis test. *Benign versus health; †cancer versus benign; ‡cancer versus health.