Table 1: KLK6 levels in the plasma of laryngeal SCC patients and controls.

Characteristics KLK6 levels (ng/mL) value Median Interquartile range All individuals 4.76 2.34   Diagnostic category        Healthy 4.65 2.32    Benign 4.65 1.86 0.607*  Cancer 4.90 4.26 0.047†       0.014‡ Anatomical region of cancer        Glottis 4.91 4.06 0.393  Supraglottis 4.88 4.21 Disease stage        I + II 5.44 3.60 0.375  III + IV 4.76 4.48 T stage        T1 6.06 3.87 0.544  T2 4.98 5.00  T3 4.98 4.55  T4 4.60 2.62 Lymph node status        pN0 5.15 3.84 0.507  pN+ 4.77 4.49 Tumor differentiation        Well 4.65 5.09 0.637  Moderate 5.33 4.66  Poor 4.59 3.85

KLK6: kallikrein 6. Comparisons of the plasma KLK6 levels between two independent sample cohorts were assessed by the Mann-Whitney test, and those among more than two independent cohorts were assessed by the Kruskal-Wallis test. *Benign versus health; †cancer versus benign; ‡cancer versus health.