Research Article

CLCA2 as a Novel Immunohistochemical Marker for Differential Diagnosis of Squamous Cell Carcinoma from Adenocarcinoma of the Lung

Table 3

CLCA2 protein expression status in 161 primary squamous cell carcinomas of the lung and 235 primary adenocarcinomas of the lung.

HistologyCLCA2 protein expressionSensitivitySpecificity
Positive ( = 106)Negative ( = 290) valuea

Squamous cell carcinoma ( = 161)104 (64.6%)57 (35.4%)<0.000164.6%99.1%
Adenocarcinoma ( = 235)2 (0.9%)233 (99.1%)

Chi-square test.