Mass Spectrometric Screening of Ovarian Cancer with Serum Glycans

Figure 2

ROC curves of the classification in the training set. ROC curves were derived with the combination of biomarkers from both 10% ACN and 20% ACN fractions. The cut-off threshold of each biomarker was set to meet the standard sensitivities (below the plot). A scoring system with weighting factors based on AUC of each biomarker integrated information from multiple biomarkers, providing ROC curves. Standards for the determination of the cut-off values were displayed below the plot (Sen70, sensitivity 70%; A, AUC, Sen 80, sensitivity 80%; EQ, sensitivity = specificity).