Research Article
Mass Spectrometric Screening of Ovarian Cancer with Serum Glycans
Table 4
Representative sensitivities and specificities obtained from the training set.
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Note. Biomarkers used in this classification were denoted in Table 3. Cut-off values of each biomarker were determined according to the standard sensitivity 70%. To combine multiple biomarkers for the screening, a classification score was calculated on the basis of the cut-off values and weighting factors. By varying the thresholds for the classification score, multiple pairs of sensitivity and specificity were acquired from the training set. Sensitivity of CA-125 level was calculated with 35 U/mL as a cut-off value. |