Molecular Targeted Approaches for Advanced BRAF V600, N-RAS, c-KIT, and GNAQ Melanomas

Table 2

Patients treated with BRAF inhibitors: frequencies of side effects.

Side effects	Frequency (%)
Arthralgia	54%
Nausea	34%
Skin erythema	28%
Vomiting	14%
Headache	13%
Fatigue	11%
Keratoacanthomas	2%
Hypertransaminasemia	2%
Alopecia	1%
QTc prolongation	1%