Research Article

Study of Leptin and Adiponectin as Disease Markers in Subjects with Obstructive Sleep Apnea

Table 1

Clinical and anthropometric characteristics of the study subjects grouped by polysomnographic diagnosis of OSA and OSA severity. Results are mean (standard deviation).

ā€‰NoMildModerateSevere

Age (years)55.8 (16.3)49.1 (17.0)53.0 (16.3)50.0 (14.8)
Height (m)1.62 (0.14)1.62 (0.10)1.59 (0.12)1.63 (0.18)
BMI (Kg/m2)40.5 (11.9)43.3 (10.5)49.8 (13.9)44.4 (16.8)
Neck size (cm)42.8 (5.2)42.2 (7.5)44.6 (4.7)44.4 (3.5)
MMP2.33 (1.19)2.59 (1.37)2.70 (1.17)2.95 (1.10)*
Saturation of O2 on air (%)94.82 (2.62)94.36 (4.32)93.33 (3.45)95.42 (2.34)
Epwoth's scale7.69 (5.48)9.60 (5.39)10.89 (7.80)12.44 (7.28)*
Sleep efficiency (%)83.45 (7.84)81.44 (7.79)82.25 (10.77)81.08 (6.92)
Desaturation index 10.00 (7.45)20.06 (19.12)30.38 (20.44)49.11 (23.20)*
Total number of arousal/hr95.43 (67.09)72.73 (46.87)77.24 (62.37)69.53 (55.18)
Arousal index/hour18.39 (12.48)14.39 (9.16)16.04 (12.65)15.61 (13.89)
Basal O2 during sleep (%)92.57 (3.05)91.90 (3.71)90.18 (4.89)90.91 (4.7)
Average low O2 during all desaturation (%)88.036 (3.75)87.31 (4.24)83.75 (6.18)83.92 (5.94)
Minimum O2 value (%)65.49 (21.65)67.68 (12.87)57.90 (15.32)59.65 (13.67)
Basal heart rate (bpm)72.30 (8.62)73.57 (10.72)79.37 (9.59)75.32 (11.06)
Slowest heart rate (bpm)44.48 (8.40)40.23 (8.39)45.21 (9.02)44.41 (11.61)
Fastest heart rate (bpm)100.69 (12.46)101.51 (11.50)102.08 (11.12)104.61
Respiratory disturbance index2.6 (1.6)10.3 (3.8)18.0 (6.9)48.9 (13.1)*
Hb (g/L)136.26 (19.17)130.38 (18.95)130.88 (25.30)145.47 (18.53)
WBC ( /L) 8.16 (3.39)8.75 (2.57)9.73 (1.71)8.80 (4.01)

for trend <0.05.
MMP: modified Mallampati score, BMI: body mass index, bpm: beats per minute, Hb: hemoglobin, O2: oxygen, and WBC: white blood cells.