Research Article
Study of Leptin and Adiponectin as Disease Markers in Subjects with Obstructive Sleep Apnea
Table 3
Correlations of adiponectin, leptin, and leptin : adiponectin ratio with clinical parameters and polysomnographic variables.
| | Variable | Adiponectin (ng/mL) | Leptin | Leptin : adiponectin ratio |
| | Adiponectin (ng/mL) | | 0.18
** (0.042) | −0.50** (<0.0001) | | Leptin (ng/mL) | 0.18
** (0.042) | | 0.72
** (<0.0001) | | Leptin : adiponectin ratio | −0.50** (<0.0001) | 0.72
** (<0.0001) | | | Age (years) | 0.34
** (<0.0001) | 0.15 (0.090) | −0.10 (0.269) | | BMI (Kg/m2) | −0.005 (0.960) | 0.54
** (<0.0001) | 0.43
** (<0.0001) | | Height (m) | −0.23** (0.007) | −0.30** (0.001) | −0.13 (0.157) | | Waist (cms) | 0.06 (0.539) | 0.38
** (<0.001) | 0.23
** (0.017) | | Neck (cms) | −0.19** (0.025) | 0.05 (0.613) | 0.11 (0.216) | | MMP | −0.02 (0.858) | −0.07 (0.425) | −0.09 (0.346) | | SBP (mm/Hg) | −0.07 (0.461) | 0.11 (0.217) | 0.12 (0.186) | | DBP (mm/Hg) | −0.02 (0.838) | −0.03 (0.757) | 0.03 (0.782) | | Saturation of O2 on air (%) | −0.23** (0.010) | −0.28** (0.002) | −0.06 (0.531) | | Total number of arousal | 0.19
** (0.030) | 0.08 (0.392) | −0.10 (0.299) | | Arousal index/hour | 0.17
** (0.046) | 0.12 (0.202) | −0.06 (0.534) | | Basal O2 during sleep (%) | −0.06 (0.529) | −0.13 (0.167) | −0.10 (0.298) | | Average low O2 during all desaturations | −0.09 (0.303) | −0.10 (0.263) | −0.05 (0.589) | | minimum O2 value | 0.05 (0.584) | −0.11 (0.209) | −0.14 (0.130) | | RDI | −0.20** (0.018) | −0.09 (0.340) | 0.05 (0.617) | | Basal heart rate (bpm) | 0.14 (0.133) | 0.26
** (0.005) | 0.13 (0.171) | | Slowest heart rate (bpm) | 0.04 (0.659) | 0.04 (0.676) | 0.03 (0.763) | | Fastest heart rate (bpm) | 0.03 (0.737) | 0.15 (0.109) | 0.09 (0.343) |
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Significant correlations are indicated by ** and BOLD type.
BMI: body mass index, MMP: modified Mallampati score, SBP: systolic blood pressure, DBP: diastolic blood pressure, RDI: respiratory disturbance index.
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