Study of Leptin and Adiponectin as Disease Markers in Subjects with Obstructive Sleep Apnea

Table 4

Binary logistic regression of the determinants of obstructive sleep apnea in the study subjects.

Variable	Crude odds ratio	𝑃	Odds ratio after inclusion of age, sex, and BMI	𝑃
Adiponectin (ng/mL)	0.947 (0.898–0.997)	0.039	0.925 (0.871–0.983)	0.012
Leptin (ng/mL)	0.998 (0.990–1.006)	0.589	0.994 (0.985–1.004)	0.225
Leptin : adiponectin ratio	0.993 (0.948–1.041)	0.772	0.982 (0.933–1.032)	0.468
BMI (Kg/m^2)	1.034 (0.990–1.081)	0.131	1.035 (0.989–1.083)*	0.137
Waist circumference (cm)	1.005 (0.983–1.028)	0.679	1.005 (0.983–1.028)*	0.645
MMP	1.471 (1.087–1.855)	0.022	1.36 (1.12–1.869)	0.031
Neck size (cm)	1.13 (1.004–1.240)	0.042	0.997 (0.933–1.065)	0.113
HOMA-IR	1.16 (1.013–1.307)	0.03	1.024 (0.936–1.120)	0.607

∗Only age and sex included in model.
BMI: body mass index, MMP: modified Mallampati score, HOMA-IR: homeostasis model assessment of insulin resistance.