Table 3: Association of haplotypes in the MTHFR gene with risk of T2DM.

Haplotype*Cases, %Controls, %OR (95% CI)OR (95% CI)

CTTTGA34.932.21.001.00
CTCCGA26.935.30.73 (0.60–0.88)0.71 (0.58–0.87)
ATTCGC17.312.51.22 (0.95–1.56)1.20 (0.92–1.55)
ACTCAC8.68.20.92 (0.67–1.25)0.93 (0.67–1.29)
CTTCGA6.78.80.79 (0.57–1.10)0.80 (0.56–1.13)

In the order rs12121543, rs13306553, rs9651118, rs1801133, rs2274976, and rs1801131.
Adjusted for age. Adjusted for age, sex, BMI, and hypertension.