Table 4: Association between MTHFR polymorphisms and serum tHcy levels in health controls.

SNPM/mtHcy (mol/L)
MMMmmm

rs12121543C/A12.5 (10.1–14.6)11.8 (9.7–13.5)10.4 (8.5–14.1)0.21
rs13306561T/C12.1 (9.9–14.4)10.5 (8.4–13.7)12.3 (10.0–14.4)0.87
rs13306553T/C12.1 (10.0–14.4)12.4 (10.0–14.4)9.1 (8.1–11.8)0.45
rs9651118T/C12.5 (9.8–14.6)12.1 (10.1–14.1)11.3 (9.3–13.4)0.02
rs1801133C/T11.3 (9.3–13.7)12.8 (10.9–14.4)11.9 (9.5–16.6)0.0002
rs2274976G/A12.1 (9.9–14.4)12.3 (10.0–14.1)10.7 (8.4–13.7)0.84
rs4846048A/G12.4 (10.0–14.4)11.4 (9.5–13.3)10.7 (8.6–20.1)0.28
rs1801131A/C12.5 (10.1–14.6)11.8 (9.7–13.6)10.8 (8.6–14.1)0.26
rs17037396C/T12.1 (9.9–14.2)12.1 (10.0–14.6)13.7 (12.5–15.2)0.67

Adjusted for age, sex, BMI, and hypertension.
M indicates major allele; m indicates minor allele.