A Comparison of KL-6 and Clara Cell Protein as Markers for Predicting Bronchopulmonary Dysplasia in Preterm Infants

Table 5

KL-6 (ng/mL) and CC16 (pg/mL) cut-off levels for predicting BPD.

	Age (d)*	Cut-off	Sensitivity (%)	Specificity (%)	Predictive value (%)		AUC
					Positive	Negative
KL-6	7	≥89.347	83.3	89.8	80.0	91.7	0.911
	14	≥79.261	91.7	89.8	81.5	95.7	0.952
CC16	7	≤317.26	71.4	62.5	51.6	80.5	0.734
	14	≤358.35	75.5	87.5	67.7	90.3	0.855
KL-6 + CC16	7		100	96.7	100	100	0.932
	14		100	97.1	100	100	0.974

Postpartum.