Clinical Study

HLA-G Polymorphism (rs16375) and Acute Rejection in Liver Transplant Recipients

Table 2

Distribution of HLA-G 14 bp insertion/deletion (rs16375) genotype/allele in acute rejection (AR) and nonacute rejection (NAR) groups.

HLA-G genotypeARs (%)NARs (%) valueOR (95% CI)

−14/−146 (29)29 (37)0.480.69 (0.21–2.18)
−14/+1413 (62)37 (47)0.211.84 (0.62–5.54)
+14/+142 (9)13 (16)0.340.53 (0.08–2.85)

−14/−146 (29)29 (37)0.480.69 (0.21–2.10)
−14/+14 and
+14/+14
15 (71)50 (63)

HLA-G allele
 −14 insertion25 (60)95 (60)0.940.98 (0.46–2.07)
 +14 deletion17 (40)63 (40)