Elevated Plasma Stromal-Cell-Derived Factor-1 Protein Levels Correlate with Severity in Patients with Community-Acquired Pneumonia

Table 1

Laboratory data of both controls and patients with community-acquired pneumonia (CAP) before and after they received treatment^a.

Clinical variable	Controls (); Median (range)	Before antibiotic treatment (); Median (range)	After antibiotic treatment (); Median (range)	value; UT/C^b	value; UT/T^c
Age	59.4 ± 1.5^d	59.5 ± 2.6
Gender
Male	36 (60%)	37 (60.7%)
Female	24 (40%)	24 (39.3%)
CRP (mg/L)	3 (1–17)	86 (7–274)	9 (3–113)
WBCs (cells/mm^3)	5860 (3110–10190)	10890 (3560–32480)	8450 (3460–22340)
Neutrophils (cells/mm^3)	3530 (1738–6046)	8673 (1032–29686)	5484 (1518–21155)
PSI score
Class I		13 (21.3%)
Class II		13 (21.3%)
Class III		13 (21.3%)
Class IV		18 (29.5%)
Class V		4 (6.6%)
CURB-65 score
0		26 (42.6%)
1		17 (27.9%)
2		18 (29.5%)
APACHE II score
<15		48 (78.7%)
≥15		13 (21.3%)

CRP: C-reactive protein; WBCs: white blood cells; C: controls; UT: patients with CAP before they received antibiotic treatment; T: patients with CAP after they received antibiotic treatment.
^a was considered significant.
^bThe statistical difference was analyzed by the Mann-Whitney test.
^cThe statistical difference was analyzed by the Wilcoxon signed-rank test.
^dMean ± SD.