Impact of Molecular Testing in the Diagnosis of Thyroid Fine Needle Aspiration Cytology: Data from Mainland China

Table 3

Diagnostic values of FNA cytology, BRAF testing, or a combination of both for detecting PTC.

Diagnostic modality	SN	SP	PPV	NPV	AC
Cytology^a	60.3%	100%	100%	44.4%	69.9%
Cytology^b	87.3%	95.0%	98.2%	74.1%	89.2%
BRAF testing	65.1%	100%	100%	47.6%	73.5%
Combined^a	85.7%	100%	100%	69.0%	89.2%
Combined^b	90.5%	95.0%	98.3%	80.0%	91.6%

aCytology diagnosis of malignant was taken as the diagnostic threshold.
bCytology diagnosis of suspicious malignant was taken as the diagnostic threshold.
SN: sensitivity; SP: specificity; PPV: positive predictive value; NPV: negative predictive value; AC: accuracy.