Two Polymorphisms in the Fractalkine Receptor CX3CR1 Gene Influence the Development of Atherosclerosis: A Meta-Analysis

Table 4

Estimated haplotype frequencies and linkage disequilibrium analysis of the included studies.

First author	Estimated haplotype frequencies (cases)				Estimated haplotype frequencies (controls)
	V249 T280	V249 M280	I249 T280	I249 M280	V249 T280	V249 M280	I249 T280	I249 M280
McDermott [13, 14]	0.7817	0	0.0838	0.1345	0.7042	0	0.0986	0.1972	1	0.5848
Moatti [15]	0.7980	0	0.0993	0.1026	0.7149	0	0.1345	0.1506	1	0.4445
Gugl [8]	0.7317	0	0.0904	0.1778	0.7416	0	0.0706	0.1879	1	0.6638
McDermott [13, 14]	0.7304	0	0.1324	0.1373	0.7018	0	0.1157	0.1825	1	0.5253
Ghilardi [7]	0.7407	0	0.1481	0.1111	0.7255	0	0.1225	0.1520	1	0.4736
Hattori [44]	0.9318	0.0256	0.0065	0.0361	0.9444	0.0082	0.0033	0.0441	0.9270	0.7743
Niessner [17, 18]	0.7332	0.0016	0.1113	0.1540	0.7564	0	0.0998	0.1439	1	0.5217
Apostolakis [6, 43]	0.7214	0	0.1500	0.1286	0.7000	0	0.1212	0.1788	1	0.508
An [24]	0.8241	0	0.0833	0.0926	0.7187	0	0.1250	0.1562	1	0.4733
Nassar-a [16]	0.7067	0.0171	0.1440	0.1321	0.6544	0	0.1376	0.2081	1	0.4974
Nassar-b [16]	0.6250	0.0203	0.1622	0.1925	0.6544	0	0.1376	0.2081	1	0.4974
Zhao [23]	0.7138	0	0.1478	0.1384	0.6729	0	0.1353	0.1918	1	0.4882
Singh-a, b [21, 22]	0.7559	0.0542	0.1402	0.0497	0.6967	0	0.1050	0.1983	1	0.5682
Singh-c [21, 22]	0.7739	0.0413	0.1304	0.0543	0.6967	0	0.1050	0.1983	1	0.5682
Total	0.7477	0.0091	0.1120	0.1312	0.7224	0.0006	0.1050	0.1720	0.9950	0.5394

and statistics refer to control groups.