The Use of Humoral Responses as a Marker of CMV Burden in HIV Patients on ART Requires Consideration of T-Cell Recovery and Persistent B-Cell Activation

<div>Levels of antibodies in HIV patients over 10 years of ART and in controls. Dotted lines indicated mean levels in controls. Solid lines indicate trends over time in HIV patients (based on position of mean). Levels of antibody reactive with CMV lysate (a), CMVgB (b), CMV IE-1 (c), and EBV-VCA (e) antigens increase in the first year of ART. Levels of HIVgp41 antibody decrease in a linear trend from commencement of ART.</div>

Disease Markers

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Figure 1

Figure 1: The Use of Humoral Responses as a Marker of CMV Burden in HIV Patients on ART Requires Consideration of T-Cell Recovery and Persistent B-Cell Activation 

Figure 1 | The Use of Humoral Responses as a Marker of CMV Burden in HIV Patients on ART Requires Consideration of T-Cell Recovery and Persistent B-Cell Activation 