Stepwise Application of Urine Markers to Detect Tumor Recurrence in Patients Undergoing Surveillance for Non-Muscle-Invasive Bladder Cancer

Table 2

Single test performances in detecting recurrences and high risk recurrences in patients undergoing surveillance of non-muscle-invasive bladder cancer (NMIBC). Values are given in %. Pos: positive, PPV: positive predictive value, NPV: negative predictive value, FISH: fluorescence in situ hybridization, and NMP22: nuclear matrix protein 22.

Test	pos	Sensitivity total (sensitivity high risk tumors)	Specificity	PPV	NPV total (NPV high risk tumors)	Accuracy
Cytology	176	69.5 (86.0)	75.5	50.5	87.3 (97.7)	73.3
FISH	203	74.3 (90.0)	69.6	46.8	88.2 (98.2)	70.8
uCyt+	191	66.4 (72.0)	70.1	44.5	85.3 (95.2)	69.2
NMP22	268	70.3 (80.0)	49.9	33.6	82.3 (95.3)	55.4