Helicobacter pylori Antibody Titer and Gastric Cancer Screening

Figure 6

Modified schematic diagram of the ABC method considering the antibody titer as a continuous variable. Groups A, B, and C can each be divided into two subgroups based on antibody titer. The color gradation shows schematically the risk for gastric cancer. In Group A, the incidence of gastric cancer in the high-negative antibody subset is higher than that in the low-negative antibody titer subset. In Group B, the incidence of gastric cancer (typically diffuse-type cancer) in the high-positive titer antibody subset is higher than that in the low-positive titer antibody subset. In Group C, the HR of gastric cancer (typically intestinal-type cancer) is higher in low-positive titer subjects than in high-positive titer subjects.