Assessment of Cell-Cycle Arrest Biomarkers to Predict Early and Delayed Acute Kidney Injury

Table 1

Patient characteristics.

	No AKI; ( = 75)	AKI; ( = 19)
Age, years	50 (28, 65)	66 (52, 72)	0.003
Female gender	25 (33%)	3 (16%)	0.17
APACHE II score	15 (11, 19)	19 (13, 24)	0.03
Baseline creatinine, µmol/L	81 (67, 91)	83 (71, 88)	0.64
True baseline creatinine available	55 (73%)	10 (53%)	0.08
Time from ICU admission to first urine sample, hours	11 (5.2, 23)	5.9 (3, 14)	0.13
Comorbidity
Diabetes	7 (9%)	4 (21%)	0.22
Cardiovascular disease	21 (28%)	11 (58%)	0.01
Pulmonary disease	7 (9%)	1 (5%)	1.0
Gastrointestinal/liver disease	2 (3%)	3 (16%)	0.05
Any malignancy	11 (15%)	3 (16%)	1.0
Admission diagnosis
Neurologic	5 (5%)	1 (5%)	1.0
Respiratory	16 (21%)	4 (21%)	1.0
Cardiovascular	2 (3%)	5 (26%)	0.003
Trauma	37 (49%)	7 (37%)	0.33
Gastrointestinal	3 (4%)	1 (5%)	1.0
Sepsis	13 (17%)	1 (5%)	0.29
Outcome
ICU length of stay, days	5 (3, 9.8)	4 (2.9, 7.5)	0.51
ICU mortality	4 (5%)	2 (11%)	0.60
30-day mortality	8 (11%)	4 (21%)	0.25

Values are median (interquartile range) or (%).