Assessment of Cell-Cycle Arrest Biomarkers to Predict Early and Delayed Acute Kidney Injury
Table 4
Association between change in level of urinary TIMP-2 × IGFBP7 and clinical factors.
Variable
Not adjusted
Adjusted
Coefficient (SE)
Coefficient (SE)
Age (per year)
0.03 (0.03)
0.32
Female gender
−0.85 (1.42)
0.55
APACHE II score (per point)
0.22 (0.09)
0.02
0.15 (0.09)
0.10
AKI within 48 hours
3.05 (1.59)
0.06
1.86 (1.59)
0.24
Comorbidities
GI/liver
−1.07 (2.90)
0.71
Malignancy
−0.77 (1.83)
0.68
Cardiovascular
1.96 (1.36)
0.15
Diabetes
5.51 (1.94)
0.006
4.51 (1.96)
0.02
Pulmonary
−0.19 (2.33)
0.94
Admission diagnosis
Gastrointestinal
−0.73 (3.23)
0.82
Cardiovascular
−1.08 (2.48)
0.67
Neurologic
−1.04 (2.90)
0.72
Trauma
1.22 (1.30)
0.35
Respiratory
−0.70 (1.59)
0.66
Sepsis
−0.23 (1.83)
0.90
The adjusted regression coefficients, standard errors (SE), and values were estimated from a multiple linear regression model. Multivariate regression includes variables chosen from univariate comparison where .
