Prognostic Value of Pentraxin-3 Level in Patients with STEMI and Its Relationship with Heart Failure and Markers of Oxidative Stress
Table 1
Baseline clinical characteristics of patients according to PTX3 level at 24 h after the onset of myocardial infarction.
Characteristics
PTX3/24 h tertile
P value*
First tertile
Second tertile
Third tertile
n = 87
n = 89
n = 86
Age (years)
58.1 (49.0; 75.0)
63.7 (48.8; 79.7)
68.5 (53.0; 79.8)
<0.001
Female sex
17 (19.5)
30 (33.7)
30 (34.9)
0.041
Systolic BP (mmHg)
140 (105; 180)
140 (101; 190)
140 (85; 180)
0.411
Diastolic BP (mmHg)
80 (60; 105)
79 (55; 105)
80 (50; 97)
0.278
BMI
28.4 (23.8; 36.4)
27.7 (22.7; 35.1)
27.1 (21.1; 34.5)
0.096
Prior instability
33 (37.9)
27 (30.3)
23 (26.7)
0.273
Hypertension
53 (60.9)
52 (58.4)
53 (61.6)
0.902
Diabetes mellitus
17 (19.5)
19 (21.3)
32 (37.2)
0.016
Dyslipoproteinemia
80 (92.0)
69 (77.5)
71 (82.6)
0.023
History of MI
8 (9.2)
11 (12.4)
14 (16.3)
0.371
COPD
3 (3.4)
6 (6.7)
3 (3.5)
0.505
ACE inhibitors
19 (21.8)
26 (29.2)
20 (23.3)
0.490
Beta blockers
18 (20.7)
26 (29.2)
28 (32.6)
0.188
Statins
15 (17.2)
19 (21.3)
18 (20.9)
0.752
ARBs
9 (10.3)
3 (3.4)
9 (10.5)
0.105
Initial TIMI flow
0.055
0
41 (47.1)
58 (65.2)
53 (61.6)
1
9 (10.3)
13 (14.6)
7 (8.1)
2
18 (20.7)
7 (7.9)
13 (15.1)
3
19 (21.8)
11 (12.4)
13 (15.1)
Final TIMI flow
0.018
0
0 (0.0)
4 (4.5)
1 (1.2)
1
0 (0.0)
0 (0.0)
2 (2.3)
2
4 (4.6)
12 (13.5)
9 (10.5)
3
83 (95.4)
73 (82.0)
74 (86.0)
LVEDP (mmHg)
23 (11; 34)
26 (13; 38)
27 (13; 40)
0.006
LVEF (%)
55 (40; 68)
52 (34; 70)
45 (25; 62)
<0.001
Killip
<0.001
I
74 (85.1)
70 (78.7)
48 (55.8)
II
12 (13.8)
18 (20.2)
23 (26.7)
III + IV
1 (1.1)
1 (1.1)
15 (17.4)
Acute heart failure
13 (14.9)
19 (21.3)
38 (44.2)
<0.001
Acute kidney injury
6 (6.9)
2 (2.2)
12 (14.0)
0.011
30day mortality
0 (0.0)
1 (1.1)
9 (10.5)
<0.001
1-year mortality
0 (0.0)
4 (4.5)
18 (20.9)
<0.001
All categorical variables represented as (%) and continuous variables as median (the 5th; 95th percentiles). *P values from the Kruskal-Wallis test or maximum-likelihood test (categorical variables). BP: blood pressure; BMI: body mass index; MI: myocardial infarction; COPD: chronic obstructive pulmonary disease; ACE: angiotensin-converting enzyme; ARBs: antagonists for the type-2 receptor of angiotensin II; TIMI: thrombolysis in myocardial infarction; LVEDP: left ventricular end-diastolic pressure; LVEF: left ventricular ejection fraction; Killip: Killip classification of heart failure.
