Prognostic Value of Pentraxin-3 Level in Patients with STEMI and Its Relationship with Heart Failure and Markers of Oxidative Stress
Table 3
Laboratory parameters measured upon admission: the patients were divided according to PTX3 level in 24 h after the onset of chest pain.
Laboratory parametera
PTX3/24 h tertiles
P value*
First tertile
Second tertile
Third tertile
Leukocytes
11.7 (7.4; 18.1)
11.7 (6.6; 18.8)
12.9 (7.7; 22.4)
0.043
Glycaemia (mmol/L)
7.4 (5.3; 16)
8.4 (6.1; 13)
8.4 (5.8; 20)
0.009
Cholesterol (mmol/L)
5.5 (3.7; 7.3)
4.9 (3.5; 7.1)
5.2 (3.1; 7.2)
0.015
Triglycerides (mmol/L)
2.2 (0.8; 6.2)
1.6 (0.7; 3.7)
1.4 (0.5; 3.8)
<0.001
HDL (mmol/L)
1.2 (0.8; 1.7)
1.2 (0.8; 2.1)
1.5 (0.6; 2.0)
<0.001
LDL (mmol/L)
3.2 (1.7; 4.8)
2.7 (1.6; 5.1)
3.1 (1.2; 4.6)
0.024
Creatinine (mol/L)
83 (59; 119)
87 (60; 138)
90 (62; 151)
0.033
Uric acid (mol/L)
325 (206; 475)
303 (180; 488)
359 (198; 642)
0.013
PTX3 (ng/mL)
0.6 (0.2; 2.0)
1.0 (0.4; 3.0)
1.5 (0.3; 7.9)
<0.001
BNP (pg/mL)
46.1 (15.0; 179)
81.8 (15.3; 489)
106.3 (15.1; 605)
<0.001
TNF-α (pg/mL)
1.4 (1.1; 3.7)
3.3 (1.9; 4.1)
2.9 (1.7; 12)
0.399
MDA (mol/L)
0.6 (0.3; 1.4)
0.5 (0.3; 1.1)
0.6 (0.2; 1.2)
0.462
8-OHdG (ng/mL)
7.1 (4.5; 9.5)
7.3 (4.5; 11)
8.3 (5.2; 14)
<0.001
FRAP (mol/L)
910 (645; 1 309)
828 (467; 1 330)
987 (493; 1 589)
0.052
Cysteine (mol/L)
260 (192; 326)
259 (203; 348)
263 (163; 391)
0.924
Homocysteine (mol/L)
9.5 (5.6; 16)
10.6 (5.5; 18)
9.9 (4.0; 20)
0.539
Cysteinylglycine (mol/L)
41.5 (30.5; 62.1)
40.2 (29.3; 59.8)
41.1 (22.3; 58.2)
0.182
Glutathione (mol/L)
2.2 (1.1; 3.3)
2.3 (1.3; 3.3)
2.1 (1.0; 3.7)
0.402
Values are shown as the median (the 5th; 95th percentiles). *P value based on the Kruskal-Wallis test. aLaboratory parameters were analyzed upon hospital admission. HDL: high density lipoprotein; LDL: low density lipoprotein; PTX3: pentraxin-3; BNP: B-type natriuretic peptide; TNF-α: tumor necrosis factor alpha; MDA: malondialdehyde; 8-OHdG: 8-hydroxy-2′-deoxyguanosine; FRAP: ferric-reducing ability of plasma.
