Prognostic Value of Pentraxin-3 Level in Patients with STEMI and Its Relationship with Heart Failure and Markers of Oxidative Stress

Table 6

ROC analyses for prediction of 30-day and 1-year mortalities according to the TIMI and GRACE risk scores and levels of PTX3 at 24 h after the onset of myocardial infarction and upon admission.

Marker	AUC (95% CI)	P value	AUC (95% CI)	P value
	30-day mortality		1-year mortality
TIMI	0.795 (0.741–0.842)	<0.001	0.691 (0.582–0.800)	<0.001
GRACE	0.841 (0.717–0.966)	<0.001	0.783 (0.672–0.893)	<0.001
PTX3	0.873 (0.801–0.945)	<0.001	0.835 (0.769–0.900)	<0.001
BNP	0.812 (0.684–0.941)	<0.001	0.812 (0.715–0.909)	<0.001
TIMI + PTX3	0.847 (0.797–0.888)	<0.001	0.761 (0.669–0.853)	<0.001
GRACE + PTX3	0.851 (0.730–0.972)	<0.001	0.791 (0.682–0.901)	<0.001
PTX3/adm^*	0.652 (0.459–0.846)	0.143	0.663 (0.544–0.782)	0.016
BNP/adm^*	0.664 (0.500–0.828)	0.078	0.727 (0.605–0.848)	<0.001
TIMI + PTX3/adm^*	0.863 (0.815–0.903)	<0.001	0.760 (0.656–0.864)	<0.001
GRACE + PTX3/adm^*	0.891 (0.759–1.000)	<0.001	0.833 (0.728–0.939)	<0.001

PTX3 or BNP at time of admission.
AUC: area under curve; CI: confidence interval; TIMI: thrombolysis in myocardial infarction (risk score); GRACE: global registry of acute coronary events (risk score); PTX3: pentraxin-3 at 24 h after onset of myocardial infarction; BNP: B-type natriuretic peptide at 24 h after onset of myocardial infarction.