Tissue Kallikrein Activity, Detected by a Novel Method, May Be a Predictor of Recurrent Stroke: A Case-Control Study
Table 3
Unconditional logistic regression analysis for stroke and TK activity.
Group measure
Quartile 1
Quartile 2
Quartile 3
Quartile 4
TK activity, Eu/mL
<1.600
1.600–1.936
1.936–2.052
>2.052
Total stroke
145
82
30
64
Unadjusted (OR)†
1
0.11 (0.06–0.21)
0.03 (0.013–0.05)
0.07 (0.04–0.12)
Adjusted (OR)†
1
0.14 (0.07–0.29)
0.02 (0.01–0.04)
0.10 (0.05–0.20)
Ischemic stroke
66
58
20
30
Unadjusted (OR)†
1
0.81 (0.52–1.27)
0.20 (0.11–0.37)
0.32 (0.19–0.52)
Adjusted (OR)†
1
1.12 (0.66–1.88)
0.30 (0.16–0.59)
0.55 (0.32–0.97)
Hemorrhagic stroke
79
24
10
34
Unadjusted (OR)†
1
0.18 (0.11–0.31)
0.07 (0.03–0.14)
0.26 (0.16–0.41)
Adjusted (OR)†
1
0.20 (0.10–0.38)
0.07 (0.03–0.16)
0.37 (0.21–0.68)
TK: tissue kallikrein; ORs: odds ratios. †ORs (95% confidence interval). Adjusted ORs have been adjusted for age, sex, presence or absence of hypertension, diabetes, hyperlipidemia, smoking, weight, BMI, SBP, DBP, total cholesterol, triglyceride, and HDL.
