Research Article
CYP7A1 Gene Polymorphism Located in the 5′ Upstream Region Modifies the Risk of Coronary Artery Disease
Table 2
Distribution of the genotypes and alleles of the rs7833904 polymorphism in the group of coronary artery disease (CAD) patients and controls.
| | Genotype/allele | CAD
| Control
| Model | OR (CI 95%), | | (%) | (%) |
| | TT | 45 (22.50%) | 74 (33.78%) | Additive | 1 | | AT | 98 (49.00%) | 101 (46.12%) | 1.59 (1.00–2.53) 0.06 | | AA | 57 (28.50%) | 44 (20.10%) | 2.13 (1.24–3.66), 0.008* | AA + AT
TT | 155 (77.50%)
45 (22.50%) | 145 (66.21%)
74 (33.78%) | Dominant | 1.76 (1.14–2.71), 0.014*
1 | AT + TT
AA | 143 (71.50%)
57 (28.50%) | 175 (79.90%)
44 (20.10%) | Recessive | 0.63 (0.40–0.99), 0.058
1 |
| | A | 212 (53.00%) | 189 (43.15%) | | 1.49 (1.13–1.95), 0.005* vs T | | T | 188 (47.00%) | 249 (56.85%) | | 0.67 (0.51–0.88), 0.005* vs A |
|
|
*—statistically significant differences between groups.
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