Research Article

Identification of Novel Epigenetic Markers of Prostate Cancer by NotI-Microarray Analysis

Table 4

Detection and discrimination of aggressive/nonaggressive prostate cancer and adenoma using the set of 16 selected markers.

UseSet of markers

Detection of aggressive/nonaggressive cancer and adenomaBHLHE40, FOXP1, LOC285205, ITGA9, CTDSPL (RBSP3), FGF12
Sp = 94% Sn = 94% Ac = 94%

Discrimination between aggressive cancer and nonaggressive cancer/adenomaLOC440944/SETD5, VHL, CLCN2, OSBPL10/ZNF860, LMCD1
Sp = 97% Sn = 100% Ac = 97%

Discrimination between nonaggressive cancer and adenomaFAM19A4, CAND2, MAP4, KY, LRRC58
Sp = 73% Sn = 93% Ac = 83%

Note. Sp/Sn/Ac: specificity/sensitivity/accuracy of the set.