Effects of Long-Term Statin Therapy in Coronary Artery Disease Patients with or without Chronic Kidney Disease

Table 3

Effects of statins on clinical outcomes of different group of patients.

Variables	Long-term statins	No statin	Extent of reduction	value
CAD-only patients
MACE	89/197 (45.2%)	21/45 (46.7%)	1.5%	0.987
All-cause death	17/197 (8.6%)	9/45 (20%)	11.4%	0.049
Cardiac death	14/197 (7.1%)	8/45 (17.8%)	10.7%	0.049
CAD + CKD patients
MACE	77/170 (45.3%)	104/158 (65.8%)	20.5%	<0.001
All-cause death	18/170 (10.6%)	62/158 (39.2%)	28.6%	<0.001
Cardiac death	12/170 (7.1%)	55/158 (34.8%)	27.7%	<0.001
CKD-only patients
MACE	14/41 (34.1%)	22/106 (20.8%)	−13.3%	0.142
All-cause death	2/41 (4.9%)	7/106 (6.6%)	1.7%	0.99
Cardiac death	0/41 (0%)	4/106 (3.8%)	3.8%	0.48

CAD, coronary artery disease; CKD, chronic kidney disease; MACE, major adverse cardiovascular event.