Disease Markers

Research Article

Prognostic Utility of Vitamin D in Acute Coronary Syndrome Patients in Coastal Norway

Table 3

(a) Baseline characteristics of the female population arranged according to the quartiles of 25(OH)D. (b) Baseline characteristics of the male population arranged according to the quartiles of 25(OH)D.

(a)


Characteristics (%)	Quartiles of 25(OH)D				value
Characteristics (%)	Q1	Q2	Q3	Q4	value

25(OH)D (nmol/L)	28.8 ± 5.6	43.2 ± 3.9	55.6 ± 3.4	76.1 ± 12.3	<0.001
25(OH)D (ng/mL)	11.5 ± 2.2	17.3 ± 1.6	22.2 ± 1.4	30.4 ± 4.9	<0.001
Age, years	75.5 ± 14.3	75.8 ± 12.9	75.0 ± 12.1	70.9 ± 12.8	0.058
Smoking status, (%)					0.384
Current smoker, (%)	18 (21.7)	14 (16.7)	10 (11.9)	17 (20.2)
Past smoker, (%)	13 (15.7)	21 (25.0)	17 (20.2)	21 (25.0)
Never smoked, (%)	52 (62.7)	49 (58.3)	57 (67.9)	46 (54.8)
Angina pectoris, (%)	44 (53.0)	45 (53.6)	39 (46.3)	39 (46.4)	0.663
CHF, (%)
Killip class 2–4	43 (51.8)	26 (31.0)	20 (23.8)	17 (20.2)	<0.001
History of previous MI, (%)	30 (36.1)	25 (29.8)	25 (29.8)	22 (26.2)	0.567
CABG, (%)	6 (7.2)	3 (3.6)	8 (9.5)	3 (3.6)	0.279
PCI, (%)	1 (1.2)	2 (2.4)	7 (8.3)	8 (9.5)	0.035
Hypertension, (%)	41 (49.4)	39 (46.4)	40 (47.6)	37 (44.4)	0.917
History of DM 1, (%)	1 (1.2)	1 (1.2)	0 (0.0)	1 (1.2)	0.798
History of DM 2, (%)	11 (13.3)	12 (14.3)	13 (15.5)	9 (10.7)	0.828
STEMI, (%)	11 (13.3)	7 (8.3)	3 (3.6)	7 (8.3)	0.164
TnT release, (%)	46 (55.4)	40 (47.6)	42 (50.0)	34 (40.5)	0.277
eGFR (μmol L⁻¹)	52.3 ± 18.4	54.9 ± 17.4	53.9 ± 17.8	58.9 ± 15.1	0.079
Cholesterol/statin, (%)	43 (51.8)	46 (54.8)	45 (53.6)	45 (53.6)	0.985
Beta-blocker, (%)	33 (39.8)	32 (38.1)	38 (45.2)	23 (27.4)	0.112
Known CHD, (%)	59 (71.1)	56 (66.7)	56 (66.7)	50 (59.5)	0.465
BMI (kg/m²)	25.4 ± 4.8	25.5 ± 4.6	25.2 ± 5.2	24.9 ± 4.0	0.886
BNP quartiles					0.094
Q1	17 (20.7)	20 (25.0)	17 (21.5)	27 (33.8)
Q2	19 (23.2)	23 (28.8)	20 (25.3)	19 (23.8)
Q3	15 (18.3)	21 (26.3)	23 (29.1)	21 (26.3)
Q4	31 (37.8)	16 (20.0)	19 (24.1)	13 (16.3)
hsCRP quartiles					0.995
Q1	20 (24.1)	19 (22.6)	21 (25.0)	24 (28.6)
Q2	21 (25.3)	20 (23.8)	22 (26.2)	20 (23.8)
Q3	21 (25.3)	22 (26.2)	19 (22.6)	22 (26.2)
Q4	21 (25.3)	23 (27.4)	22 (26.2)	18 (21.4)

Mean ± SD.
SD, standard deviation; 25(OH)D, 25-hydroxyvitamin D; CHF, congestive heart failure; MI, myocardial infarction; CABG, coronary artery bypass grafting; PCI, percutaneous coronary intervention; DM, diabetes mellitus; STEMI, ST-elevation myocardial infarction; TnT, troponin T; eGFR, estimated glomerular filtration rate; CHD, coronary heart disease; BMI, body mass index; BNP, B-type natriuretic peptide; hsCRP, high sensitivity C-reactive protein.

(b)


Characteristics (%)	Quartiles of 25(OH)D				value
Characteristics (%)	Q1	Q2	Q3	Q4	value

25(OH)D (nmol/L)	31.7 ± 6.0	46.3 ± 3.0	57.4 ± 3.8	79.9 ± 13.7	<0.001
25(OH)D (ng/mL)	12.7 ± 2.4	18.5 ± 1.2	23.0 ± 1.5	32.0 ± 5.5	<0.001
Age, years	63.6 ± 15.3	66.0 ± 16.3	67.8 ± 12.9	68.6 ± 12.3	0.024
Smoking status, (%)					0.211
Current smoker, (%)	53 (40.5)	44 (33.6)	37 (28.0)	34 (26.0)
Past smoker, (%)	53 (40.5)	58 (44.3)	67 (50.8)	63 (48.1)
Never smoked, (%)	25 (19.1)	29 (22.1)	28 (21.2)	34 (26.0)
Angina pectoris, (%)	46 (35.1)	48 (36.6)	60 (45.5)	54 (41.2)	0.306
CHF, (%)
Killip Class 2–4	42 (32.1)	21 (16.0)	32 (24.2)	31 (23.7)	0.026
History of previous MI, (%)	50 (38.2)	46 (35.1)	45 (34.1)	44 (33.6)	0.867
CABG, (%)	18 (13.7)	14 (10.7)	16 (12.1)	19 (14.5)	0.795
PCI, (%)	19 (14.5)	17 (13.0)	18 (13.6)	15 (11.5)	0.903
Hypertension, (%)	44 (33.6)	45 (34.4)	56 (42.4)	59 (45.0)	0.141
History of DM 1, (%)	1 (0.8)	1 (0.8)	1 (0.8)	2 (1.5)	0.894
History of DM 2, (%)	25 (19.1)	14 (10.7)	19 (14.4)	8 (6.1)	0.013
STEMI, (%)	21 (16.0)	28 (21.4)	28 (21.2)	23 (17.6)	0.610
TnT release, (%)	73 (55.7)	74 (56.5)	76 (57.6)	81 (61.8)	0.754
eGFR (μmol L⁻¹)	70.5 ± 21.7	67.0 ± 21.0	68.1 ± 20.6	65.8 ± 21.7	0.312
Cholesterol/statin, (%)	57 (43.5)	62 (47.3)	65 (49.2)	61 (46.6)	0.826
Beta-blocker, (%)	49 (37.4)	44 (33.6)	44 (33.3)	45 (34.4)	0.894
Known CHD, (%)	80 (61.1)	77 (58.8)	85 (64.4)	79 (60.3)	0.817
BMI (kg/m²)	26.1 ± 3.9	26.6 ± 4.9	26.0 ± 3.4	25.0 ± 3.5	0.014
BNP quartiles					0.545
Q1	29 (23.4)	35 (27.3)	27 (21.1)	36 (29.5)
Q2	30 (24.2)	30 (23.4)	39 (30.5)	27 (22.1)
Q3	30 (24.2)	27 (21.1)	36 (28.1)	31 (25.4)
Q4	35 (28.2)	36 (28.1)	26 (20.3)	28 (23.0)
hsCRP Quartiles					0.904
Q1	30 (22.9)	33 (25.2)	32 (24.2)	36 (27.5)
Q2	28 (21.4)	31 (23.7)	35 (26.5)	36 (27.5)
Q3	37 (28.2)	34 (26.0)	35 (26.5)	27 (20.6)
Q4	36 (27.5)	33 (25.2)	30 (22.7)	32 (24.4)