Overexpression of FRAT1 Is Associated with Malignant Phenotype and Poor Prognosis in Human Gliomas

Table 3

Univariate Cox regression analysis of possible contribution to survival^a.

Variable			Hazard ratio (95% CI)
Age	≥50 y	15	8.928 (2.363–33.734)	0.0012
	<50 y	8
Sex	Female	10	1.485 (0.609–3.625)	0.3848
	Male	13
Extent of resection	Total	14	0.428 (0.169–1.086)	0.0741
	Subtotal	9
Karnofsky performance status	≥80	17	0.741 (0.281–1.958)	0.5458
	<80	6
FRAT1 positivity	+	18	4.817 (1.307–17.751)	0.0182
	−	5
Tumor size	≥4 cm	16	3.974 (1.298–12.165)	0.0157
	<4 cm	7

CI: confidence interval.