Research Article
Postoperative CA19-9 Change Is a Useful Predictor of Intrahepatic Cholangiocarcinoma Survival following Liver Resection
Table 4
Risk factors in ICC‡ patients for overall survival by Cox multivariate analysis.
| Factors | Subgroups | | HR (95% CI) | value |
| Age (years) | >65 | | 3.881 (1.301–11.581) | 0.01 | ≤65 | | Ref. |
| PostopCA19-9 (U/mL) | Elevated (>37) | 11 | 4.41 (2.01–6.72) | <0.001 | Normalized (≤37) | 63 | Ref. |
| Perineural invasion | (+) | 45 | 3.073 (1.255–7.521) | 0.01 | (−) | 29 | Ref. |
| Resection margin | ≤1 cm | 43 | 3.152 (1.115–8.908) | 0.05 | >1 cm | 21 | Ref. |
| Lymph node metastasis | (+) | 20 | 3.427 (1.346–8.723) | 0.02 | (−) | 54 | Ref. |
|
|
ICC‡: intrahepatic cholangiocarcinoma; postopCA19-9: postoperative lowest CA19-9.
|