Research Article

CSF Levels of Angiopoietin-2 Do Not Differ between Patients with CSF Fluid Leakage Syndrome and Controls

Table 2

Overview of cerebrospinal fluid (CSF) and angiopoietin-2 (Ang-2) parameters. Q: quotient, that is, CSF to serum ratio; alb.: albumin; Ig: immunoglobulin; C: control subjects; LS: subjects with CSF leakage; LP: lymphocytic pleocytosis; N: normal; ABC: artificial blood contamination; n.a.: not applicable; and n.d.: not done.

CSF characteristicsAng-2
Cell count
per µL
CytologyCSF total protein (mg/L)Qalb
(CSF/serum × 103)
Blood-CSF barrier functionIgG
synthesis
IgA
synthesis
IgM
synthesis
Oligoclonal bandsLactate
(mmol/L)
QAng-2
(CSF/serum × 103)
QAng-2/Qalb

SubjectsLS

115.3LP111013.2ImpairedNoNoNoType IIn.d.106.88.1
223.0LP8968.8ImpairedNoNoNoType I1.8193.021.9
315.0LP102118.7ImpairedNoNoNoType III1.7403.621.6
41.3N4765.9IntactNoNoNoType I1.6203.634.5
50.3ABC290048.5n.a.NoNoNoType In.d.46.60.96
66.7LP3654.8IntactNoNoNoType In.d.803.9167.5
73.0N103315.4ImpairedNoNoNoType I1.5584.438.0
80.3ABC104417Impairedn.a.n.a.n.a.Type I1.8418.624.6
92.0N7299.9ImpairedNoNoNoType I2.0105.910.7
103.0N5629.5ImpairedNoNoNoType I1.7542.457.3

ControlsC

10.7N4045.3IntactNoNoNoType I1.7218.341.5
21.0N4136.3IntactNoNoNoType I1.9235.837.7
32.3N79614.8ImpairedNoNoNoType I2.0222.415.1
40.3N3775.4IntactNoNoNoType I1.4633.5116.5
53.3N5349.2ImpairedNoNoNoType II1.7254.427.5
60.3N65410.1ImpairedNoNoNoType I2.9332.532.8
71.0ABC2363.5IntactNoNoNoType I1.8175.350.4
81.3N3455.7IntactNoNoNoType I1.5243.543.1
93.3N3384.4IntactNoNoNoType I1.6443.1101.4
100.3N5067.2IntactNon.d.NoType I1.3371.051.5