FGF23 in Acute and Chronic Illness

Figure 2

Plot of multivariable adjusted hazard ratios according to preoperative levels of fibroblast growth factor 23: (a) mortality during follow-up, (b) acute kidney injury, (c) nonocclusive mesenteric ischaemia (NOMI), and (d) in-hospital mortality. Solid lines represent the hazard ratios (HRs) and dashed lines the respective 95% confidence intervals. The median of fibroblast growth factor 23 (FGF23) (64 relative units (RU)/mL) was chosen as the reference value (HR = 1). Data are adjusted for age, sex, mean arterial blood pressure, sinus rhythm, coronary artery disease, chronic heart failure, diabetes, serum creatinine, and serum high-sensitivity C-reactive protein. Green areas represent the range of FGF23 with HR < 1, yellow areas with HR ≥ 1 and <1.5, and red areas with HR ≥ 1.5. Reproduced with permission from Speer et al. [16].

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