The Clinical and Pathological Significance of Nectin-2 and DDX3 Expression in Pancreatic Ductal Adenocarcinomas

Table 2

Correlations of Nectin-2 and DDX3 protein expression with the clinicopathological characteristics of pancreatic ductal adenocarcinoma.

CPC	Case number	Nectin-2			DDX3
		Positive number (%)		value	Positive number (%)		value
Age (year)
≤45	22	12 (54.5)	0.000	0.986	14 (63.6)	1.535	0.215
>45	84	46 (54.8)			41 (48.8)
Sex
Male	61	33 (54.1)	0.022	0.882	31 (50.8)	0.066	0.798
Female	45	25 (55.6)			24 (53.3)
Differentiation
Well	38	16 (42.1)	4.424	0.109	14 (36.8)	9.341	0.009
Moderately	35	20 (57.1)			17 (48.6)
Poorly	33	22 (66.7)			24 (72.7)
Tumor size
≤3 cm	13	5 (38.5)	2.258	0.323	6 (46.2)	0.345	0.841
3–5 cm	68	37 (54.5)			35 (51.5)
>5 cm	25	16 (64.0)			14 (56.0)
Lymph node metastasis
No	77	34 (44.2)	12.670	0.000	35 (45.5)	4.664	0.031
Yes	29	24 (82.8)			20 (69.0)
Invasion
No	42	14 (33.3)	12.838	0.000	13 (31.0)	12.212	0.000
Yes	64	44 (68.8)			42 (65.6)
TNM stage
T1	11	4 (36.4)	13.190	0.004	3 (27.3)	14.848	0.002
T2	42	16 (38.1)			16 (38.1)
T3	37	25 (67.6)			22 (59.5)
T4	16	13 (81.3)			14 (87.5)

CPC: clinical and pathological characteristics.