Clinical Study
The Relationship between Clinical Feature, Complex Immunophenotype, Chromosome Karyotype, and Outcome of Patients with Acute Myeloid Leukemia in China
Table 4
Univariate Cox model for OS and RFS risk factors of MPAL, Ly+AML, and Ly−AML patients.
| Risk factors | OS | RFS | HR | 95% CI | value | HR | 95% CI | value |
| Age | 1.014 | 1.001–1.027 | 0.031 | 1.013 | 1.000–1.026 | 0.055 | Gender | 1.023 | 0.68–1.540 | 0.912 | 1.150 | 0.761–1.737 | 0.507 | WBC | 1.003 | 1.001–1.006 | 0.012 | 1.002 | 1.000–1.004 | 0.102 | BM blast | 0.996 | 0.986–1.006 | 0.429 | 0.996 | 0.986–1.006 | 0.452 | Chromosome karyotype | | | | | | | Normal | 1.000 | — | — | 1.000 | — | — | Complex | 2.409 | 1.429–4.060 | 0.001 | 2.691 | 1.591–4.553 | 0.000 | Abnormal | 1.808 | 1.018–3.211 | 0.043 | 1.718 | 0.973–3.031 | 0.062 | Immunophenotype | | | | | | | Ly−AML | 1.000 | — | — | 1.000 | — | — | Ly+AML | 1.404 | 0.768–2.565 | 0.270 | 0.808 | 0.444–1.472 | 0.486 | MPAL | 1.446 | 0.905–2.312 | 0.023 | 1.063 | 0.600–1.545 | 0.046 |
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HR: hazard ratio; CI: confidence interval; WBC: white blood cell; OS: overall survival; RFS: relapse-free survival.
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