Hiwi Promotes the Proliferation of Colorectal Cancer Cells via Upregulating Global DNA Methylation

Figure 1

Overexpression of Hiwi protein in CRC specimens. (a) and (b): immunohistochemical staining for Hiwi expression in CRC tissues () and peritumor specimens (); (c): relative mRNA level of Hiwi in the CRC specimens or the colorectal noncancer specimens by quantitative real-time RT-PCR; (d): Hiwi overexpression at protein level in the CRC or noncolon specimens, revealed by the western blot analysis; (e): percentage of Hiwi to GAPDH in protein level. The value was indicated accordingly.

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