Circulating MicroRNA-223 Serum Levels Do Not Predict Sepsis or Survival in Patients with Critical Illness

Table 3

Correlations of miR-223 serum levels at ICU admission with other laboratory markers.

Parameter	ICU patients
	Markers of liver function
Cholinesterase	0.135	n.s.
Protein	0.110	n.s.
Albumin	0.089	n.s.
GGT	0.084	n.s.
GLDH	0.116	n.s.
AP	−0.074	n.s.
INR	−0.028	n.s.
Bilirubin total	−0.014	n.s.
Bilirubin direct	0.059	n.s.
AST	0.091	n.s.
ALT	0.167	0.013
Markers of inflammation
C-reactive protein	−0.010	n.s.
Procalcitonin	−0.085	n.s.
IL-6	0.171	n.s.
IL-10	0.118	n.s.
TNF-alpha	−0.152	n.s.
Amylase	0.218	n.s.
Lipase	0.111	n.s.
Leucocyte counts	0.155	0.021
Markers of renal function
Creatinine	−0.391	<0.001
cystatin C	−0.384	<0.001
cystatin C GFR	0.379	<0.001
Urea	−0.435	<0.001
Others variables
Lactate	−0.146	0.031
NT-proCNP	−0.432	<0.001
suPAR	−0.187	0.022
Clinical scoring
APACHE-II	−0.139	n.s.
SOFA	−0.187	0.030
ICU days	−0.051	n.s.
Days alive	−0.190	n.s.

, correlation coefficient; , value; and values by Spearman rank correlation; INR, international normalized ratio; IL-6, interleukin-6; IL-10, interleukin-10; TNF, tumour necrosis factor; APACHE-II, Acute Physiology and Chronic Health Evaluation II; SOFA, Sequential Organ Failure Assessment Score.