Macrophage Migration Inhibitory Factor Promoter Polymorphisms (−794 CATT_5–8 and −173 G>C): Relationship with mRNA Expression and Soluble MIF Levels in Young Obese Subjects

Table 2

Genotype and allele frequencies of −794 (rs5844572) and −173 G>C (rs755622) MIF polymorphisms in normal-weight and obese subjects.

Polymorphism	Normal-weight	Obese	value
	n = 150 (%)	n = 100 (%)
rs5844572
Genotype			0.53
5,5	4 (3)	2 (2)
5,6	20 (13)	18 (18)
5,7	22 (15)	18 (18)
6,6	48 (32)	22 (22)
6,7	44 (29)	29 (29)
7,7	12 (8)	11 (11)
Allele			0.23
5	50 (17)	40 (20)
6	160 (53)	91 (46)
7	90 (30)	69 (35)
rs755622
Genotype			0.15
GG	68 (45)	37 (37)
GC	69 (47)	47 (47)
CC	13 (8)	16 (16)
Allele			0.07
G	205 (68)	121 (61)
C	95 (32)	79 (39)

Chi-square test .