Effect of Increased Water Intake on Urinary DNA Adduct Levels and Mutagenicity in Smokers: A Randomized Study

Table 2

Blood chemistry changes after intervention in test group versus control group.

Measure	Test	Control	All	value
	(mean ± SD)	(mean ± SD)	(mean ± SD)
Osmolality (mOsm/kg)
Baseline	32 (300.3 ± 4.7)	32 (298.8 ± 6.5)	64 (299.5 ± 5.6)
Study end	31 (297.0 ± 2.8)	31 (300.1 ± 4.1)	62 (298.5 ± 3.8)
Absolute raw change	31 (−3.4 ± 5.4)	31 (1.3 ± 7.7)	62 (−1.0 ± 7.0)
Adjusted mean change (SE)	−2.6 ± 0.6	0.5 ± 0.6		0.001

Values are shown for all subjects randomized and for whom data were available. SD, standard deviation; SE, standard error of the mean.
value determined by analysis of covariance, adjusted for baseline values (parameter and cigarettes consumption).