NT-proBNP as Early Marker of Subclinical Late Cardiotoxicity after Doxorubicin Therapy and Mediastinal Irradiation in Childhood Cancer Survivors
Table 4
Right and left ventricular TDI parameters in exposed and unexposed study groups.
Systole
Diastole ()
Diastole ()
Unexposed group
Exposed group
Unexposed group
Exposed group
Unexposed group
Exposed group
RVFW a
5.02 ± 0.2
4.2 ± 0.87
0.000
5.03 ± 0.2
4.3 ± 0.86
0.001
5.06 ± 0.4
4.3 ± 0.52
0.000
RVFW m
7.2 ± 0.51
6.4 ± 1.67
0.018
6.69 ± 0.54
5.02 ± 1.52
0.000
6.69 ± 0.54
5.02 ± 1.52
0.000
RVFW b
8.9 ± 0.25
7.71 ± 1.5
0.000
7.27 ± 0.43
6.8 ± 0.42
0.000
7.27 ± 0.34
5.9 ± 1.2
0.000
LVFW a
3.8 ± 0.29
3.4 ± 0.51
0.001
3.41 ± 0.32
2.59 ± 0.79
0.000
3.41 ± 0.32
2.59 ± 0.79
0.000
LVFW m
5.57 ± 0.36
4.58 ± 0.86
0.000
3.9 ± 0.29
3.4 ± 0.64
0.002
3.9 ± 0.37
3.4 ± 0.64
0.002
LVFW b
7.07 + 0.44
5.9 ± 1.12
0.000
5.7 ± 0.48
4.9 ± 0.95
0.001
5.07 ± 0.48
4.58 ± 0.86
0.001
RVW a, m, b: right ventricular free wall at the apical, middle, and basal parts, respectively. LVW a, m, b: left ventricular free wall at the apical, middle, and basal parts, respectively. TDI: tissue Doppler imaging. Exposed: to both chemotherapy and radiotherapy. Unexposed: only chemotherapy.
