Association of Angiotensin Converting Enzyme Insertion-Deletion Polymorphism with Hypertension in Emiratis with Type 2 Diabetes Mellitus and Its Interaction with Obesity Status
Table 4
Evaluation of T2DM and hypertension risk association with ACE DD genotype by obesity status in case-control study.
Association based on obesity status
Obesity status
ACE genotype
Groups
Logistic regression
Cases
Control
OR (95% CI)
T2DM
All together
DD
124
112
0.09
1.34 (0.96–1.87)
0.086
ID + II
153
185
Obese (BMI > 30)
DD
66
38
0.30
1.34 (0.81–2.23)
0.26
ID + II
88
68
Nonobese (BMI < 30)
DD
53
68
0.18
1.41 (0.88–2.28)
0.15
ID + II
59
107
Hypertension
All together
DD
98
136
0.86
1.02 (0.72–1.42)
0.93
ID + II
137
197
Obese (BMI > 30)
DD
50
53
0.02
0.54 (0.33–0.89)
0.01
ID + II
116
67
Nonobese (BMI < 30)
DD
46
75
0.03
1.80 (1.08–2.99)
0.02
ID + II
41
120
Data shown are numbers unless specified otherwise, Fisher exact test. All together means obese + nonobese and others about whom information on obesity status was not available.